岗位描述
Senior Scientist, Discovery Research (Gene Editing, Synthetic Biology)
Responsibilities:
1. Lead,design,and execute experiments aimed at developing next-generation genome editing strategies using synthetic biology and ,A.I. computational tools.
2. Design and optimize dynamic protein expression for genome editing in human cells.
3. Apply various synthetic biology and A.I. tools at different stages of CAR-T discovery and development.
4. Apply advanced OMICs tools for protein expression design and target engagement validations.
5. Lead from the lab to advance novel and differentiated cell therapy products toward clinical milestones,by working collaboratively with internal cross-functional teams and external partners.
6. Contribute creatively to seed innovation projects through literature review and shape execution tactics.
7. Recommends changes to project direction based on an understanding of current literature and in-house experimental data.
8. Accurately capture data in a timely manner,ensuring data integrity and protocol compliance.
Qualifications:
1. PhD in synthetic biology, computational biology or a related field.
2. Extensive experience in the development and implementation of advanced synthetic and genetic tools - such as dynamic expression control, ligand gated expression control - with particular emphasis on the applications for gene editing.
3. Experience with OMICs, A.I. for RNA, or DNA, or protein engineering, or characterization and optimization of large library systems or other technologies.
4. Good coordination and communication skills are required. Highly organized and efficient,able to work independently.
5. Strong problem-solving skill is preferred. Ability to coordinate parallel tasks across multiple projects,demonstrating prioritization.