Principal Associate, Immunology Discovery

在罗氏，我们鼓励每位同事展现真实的自己；我们欣赏独特且出众的品质。罗氏的文化鼓励积极的表达、开放的对话和真诚的连结，在这里，你将因为做自己而被重视、接纳和尊重，并得到个人的提升和职业的发展。所有的这一切，都是为了更好地预防、阻止和治愈疾病，并确保医疗资源的可及性和可持续性。欢迎加入罗氏，一个重视每种声音的地方。

职位

Primary Purpose of Job (Job Summary)

Collaborate with a group of immunology/rheumatology/nephrology scientists and associates to provide expert biology support to preclinical and clinical studies for the discovery and development of new therapeutic agents (small molecule compounds) in autoimmune and kidney diseases. Scientists/Principal Associate are responsible for contributing to new hypothesis, target identification and execution of key experiments for target validation, support project initiation and progression, and drafting and execution of research plans for nominating new projects. Commensurate with experience, scientists expected to lead and execute key in-vitro/in-vivo pharmacological experiment, cooridinate cross-functional discovery project communication and/or support projects with biology expertise. Apply skills in drug discovery to assess the potency, selectivity, safety, PK and PD of novel molecules is a plus.

Principle Roles & Responsibilities / Accountabilities

Design and implement various in vitro and in vivo studies to study potency, selectivity, and to elucidate molecular mechanism of drug action and efficacy based on scientific considerations within the context of team or project goals.

Drive or support target identifications in collaboration with translational medicine, disease biology research, and chemistry teams.

Initiate new drug discovery projects based on scientific insight with cross-functional input.

Perform scientific analysis for results interpretation and present them collaboratively.

Initiate and execute research activities related to identification and characterization of novel therapeutic targets and compounds.

Investigate and develop methods or technologies for the rapid advancement of projects.

Prepare standard operational protocols, study reports and high-quality manuscripts.

Other related duties as required, including but not limiting to organizing and maintaining laboratory and training associates and/or junior scientists.

Work in a flexible schedule to meet deadlines.

Qualification and Experience

Education/Qualifications

Ph.D. in immunology, molecular biology, mucosal immunology, nephrology, rheumatology , or a related field. PhD with medical knowledge (MD) is a plus. Industrial experience in drug discovery is a plus. Oversea education and/or training experience is preferred. Please provide an up-to-date English CV with your work experience and publications for our assessment.

Leadership Competencies

Should communicate effectively, collaborate efficiently with co-workers (cross functions and/or sites), and be able to train junior level associates and/or scientists.

Job Required Competencies

Deep knowledge of immunology and related fields is preferred.

Disease biology of the gut, kidneys and connective tissues is preferred.

Experience in drug discovery, target identification and validation is a plus.

Should be proficient in designing and conducting experiments involving the state of the art techniques within the areas of cell biology, immunology, biochemistry, molecular biology, and pharmacology.

Contribute to scientific publications.

Good communication skills in English and be capable of presenting results both inside and outside of company.

Title of positions (Scientist, Senior Scientist, and Principal Scientist) matched with candidate’s qualifications and years of experience.

One opening is available.

Travel Frequency

<25%

我们是谁

打造更健康的未来是促使我们创新的动力。全球超过100,000名员工共同致力于推进科学，确保今天和明天的人们，都能获得高质量的医疗资源。我们的努力帮助了2600多万人使用我们的药物进行治疗，我们的诊断产品运行超过300亿次检测。罗氏通过赋能探索新的可能、激发创造力并保持高标准以提供突破传统的医疗解决方案，对全球的医疗环境带去推动和影响。

让我们一起，构建更健康的未来。

罗氏提供平等的职业发展机会。